GERMINOMA IN SIBLINGS - CASE-REPORTS

Authors
AOYAMA I KONDO A OGAWA H IKAI Y
Citation
I. Aoyama et al., GERMINOMA IN SIBLINGS - CASE-REPORTS, Surgical neurology, 41(4), 1994, pp. 313-317
Citations number
43
Categorie Soggetti
Neurosciences,Surgery
Journal title
Surgical neurology → ACNP
ISSN journal
00903019
Volume
41
Issue
4
Year of publication
1994
Pages
313 - 317
Database
ISI
SICI code
0090-3019(1994)41:4<313:GIS-C>2.0.ZU;2-X
Abstract
We present the first reported cases of germinoma occurring in siblings of different genders. One tumor occurred in the left basal ganglia of a 7-year-old boy and the other in the suprasellar region of his 9-yea r-old sister. Both tumors were diagnosed as germinoma of two-cell patt ern based on light and electron microscopic studies. Possible genetic factors responsible for this phenomenon are discussed.