MORE ON CLIMBING FIBER SIGNALS AND THEIR CONSEQUENCE(S) - RESPONSE

Several themes can be identified in the commentaries. The first is tha t the climbing fibers may have more than one function; the second is t hat the climbing fibers provide sensory rather than motor signals. We accept the possibility that climbing fibers may have more than one fun ction - hence ''consequence(s)'' in the title. Until we know more abou t the function of the inhibitory input to the inferior olive from the cerebellar nuclei, which are motor structures, we have to keep open th e possibility that the climbing fiber signals can be a combination of sensory and motor signals.