MOLECULAR CHARACTERISTICS OF HUMAN PLASMA, PLATELET AND VASCULAR CELLPAI-1 - COMPARISON BETWEEN NORMAL AND THROMBOCYTEMIC SUBJECTS

Authors
PANNOCCHIA A GARIS G GIORGIANNI A STELLA S PILERI A BAZZAN M
Citation
A. Pannocchia et al., MOLECULAR CHARACTERISTICS OF HUMAN PLASMA, PLATELET AND VASCULAR CELLPAI-1 - COMPARISON BETWEEN NORMAL AND THROMBOCYTEMIC SUBJECTS, Fibrinolysis, 8, 1994, pp. 28-30
Citations number
5
Categorie Soggetti
Hematology
Journal title
Fibrinolysis → ACNP
ISSN journal
02689499
Volume
8
Year of publication
1994
Supplement
2
Pages
28 - 30
Database
ISI
SICI code
0268-9499(1994)8:<28:MCOHPP>2.0.ZU;2-F
Abstract
The recovery and stability of human platelet and plasma PAI activity i n 15 thrombocytemic patients and 15 controls was studied. In patients plasma PAI-1 is present at higher concentrations but in a less stable form. A defective stabilization of the molecule could be responsible f or the quick inactivation of PAT-I observed in thrombocytemic patients .