AN ANTIBODY FRAGMENT AGAINST PAI-1 INHIBITS PAI-1 ACTIVITY AND STIMULATES FIBRINOLYSIS IN-VITRO AND IN-VIVO

Authors
ABRAHAMSSON T BJORQUIST P DEINUM J EHNEBOM J HULANDER M LEGNEHED A MATSSON C NERME V WESTINERIKSSON A AKERBLOM B
Citation
T. Abrahamsson et al., AN ANTIBODY FRAGMENT AGAINST PAI-1 INHIBITS PAI-1 ACTIVITY AND STIMULATES FIBRINOLYSIS IN-VITRO AND IN-VIVO, Fibrinolysis, 8, 1994, pp. 55-56
Citations number
3
Categorie Soggetti
Hematology
Journal title
Fibrinolysis → ACNP
ISSN journal
02689499
Volume
8
Year of publication
1994
Supplement
2
Pages
55 - 56
Database
ISI
SICI code
0268-9499(1994)8:<55:AAFAPI>2.0.ZU;2-4
Abstract
The inhibition of PAI-1 (plasminogen activator inhibitor type 1) was s tudied in different systems, both in vivo and in vitro. The results un ambiguously show that inhibition of PAI-1 can stimulate fibrinolysis.