Pjm. Salemink et al., PROTHROMBIN TIMES AND ACTIVATED PARTIAL THROMBOPLASTIN TIMES IN TOXICOLOGY - A COMPARISON OF DIFFERENT BLOOD WITHDRAWAL SITES FOR WISTAR RATS, Comparative haematology international, 4(3), 1994, pp. 173-176
The prothrombin time (PT) and the activated partial thromboplastin tim
e (APTT) for untreated male Wistar rats were determined on the Sysmex
CA-5000 Instrument for blood taken from the orbital sinus, tail vein,
vena cava and aorta. Boxplot and statistical analysis was performed. O
nly orbital sinus puncture yields unpredictable and unacceptable varia
tion/prolongation of clotting times.