The myxomatous degenerated, prolapsed, or floppy mitral valve is the m
ost common etiology of mitral regurgitation in North American populati
ons. We performed mitral valve reconstruction for this diagnosis in 25
2 patients from 1984 to 1993. There were 165 males and 87 females rang
ing in age from 23 to 84 years (mean 64 years); 93 (37%) were greater-
than-or-equal-to 70 years. One hundred eighty-six were New York Heart
Association Functional Class III or IV and 29% (72) underwent concomit
ant coronary bypass operation. Operations included posterior leaflet r
esection, anterior leaflet resection treatment of chordal pathology by
shortening or Gore-Tex replacement, and ring annuloplasty. There were
five operative deaths for an operative mortality of 2%. The operative
risk in patients under 70 years was 1 of 159 (0.6%) and 4 of 93 (4%)
in patients older than 70 years. Ninety percent of patients are asympt
omatic in a follow-up period extending 10 years, while structural valv
e degeneration requiring reoperation at 5 years was 85%. From 1990 to
1993 there has been a less than 5% absolute incidence of structural va
lve degeneration. Mitral valve reconstruction for complicated floppy m
itral valve is feasible and offers excellent early and medium-term res
ults.