A CONCISE SYNTHESIS OF ALPHA-GLYCOSYL CYANIDES

Authors
IGARASHI Y SHIOZAWA T ICHIKAWA Y
Citation
Y. Igarashi et al., A CONCISE SYNTHESIS OF ALPHA-GLYCOSYL CYANIDES, Bioorganic & medicinal chemistry letters, 7(5), 1997, pp. 613-616
Citations number
28
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
7
Issue
5
Year of publication
1997
Pages
613 - 616
Database
ISI
SICI code
0960-894X(1997)7:5<613:ACSOAC>2.0.ZU;2-A
Abstract
A simple procedure has been developed for the synthesis of alpha-glyco syl cyanides: reactions of O-benzylated ethyl 1-thio-glycosides of L-f ucose and D-glucose, with TMSCN and MeOTf in ether exclusively gave th e corresponding alpha-glycosyl cyanides in good yields. (C) 1997 Elsev ier Science Ltd. All rights reserved.