THE EVOLUTION AND RECOGNITION OF PROTEIN-SEQUENCE REPEATS

Authors
HERINGA J
Citation
J. Heringa, THE EVOLUTION AND RECOGNITION OF PROTEIN-SEQUENCE REPEATS, Computers & chemistry, 18(3), 1994, pp. 233-243
Citations number
45
Categorie Soggetti
Computer Application, Chemistry & Engineering",Chemistry,"Computer Science Interdisciplinary Applications
Journal title
Computers & chemistry → ACNP
ISSN journal
00978485
Volume
18
Issue
3
Year of publication
1994
Pages
233 - 243
Database
ISI
SICI code
0097-8485(1994)18:3<233:TEAROP>2.0.ZU;2-A
Abstract
Many proteins sequences contain motifs which display similarity. The s imilarities between the repeats are a result of gene duplication and/o r gene fusion. The evolutionary role of repeats within protein sequenc es is considered and some repeat examples are given ranging from tande m repeats to multiple types of repeats which are sequentially interspe rsed. Existing computer methods to delineate repeats in individual pro tein sequences are discussed and a novel sensitive repeat recognition method is introduced.