A COMPUTER-PROGRAM BASED ON PARALLEL LINE ASSAY FOR ANALYSIS OF SKIN-TESTS

Citation
S. Martin et al., A COMPUTER-PROGRAM BASED ON PARALLEL LINE ASSAY FOR ANALYSIS OF SKIN-TESTS, Allergy, 52(1), 1997, pp. 97-100
Citations number
19
Categorie Soggetti
Allergy,Immunology
Journal title
ISSN journal
01054538
Volume
52
Issue
1
Year of publication
1997
Pages
97 - 100
Database
ISI
SICI code
0105-4538(1997)52:1<97:ACBOPL>2.0.ZU;2-X
Abstract
A computer program for the analysis of differences or changes in skin sensitivity has been developed. It is based on parallel line assay, an d its main features are its ability to conduct a validation process wh ich ensures that the data from skin tests conform to the conditions im posed by the analysis which is carried out (regression, parallelism, e tc.), the estimation of the difference or change in skin sensitivity, and the determination of the 95% and 99% confidence intervals of this estimation. This program is capable of managing data from independent groups, as well as paired data, and it may be applied to the compariso n of allergen extracts, with the aim of determining their biologic act ivity, as well as to the analysis of changes in skin sensitivity appea ring as a consequence of treatment such as immunotherapy.