Delirium occurs in 25-40% of patients with cancer and in as many as 85
% of patients with advanced cancer. Delirium, or acute confusion, can
be short term and reversible and differs from dementia, which is chron
ic and irreversible. Accurate assessment is critical for effective tre
atment and to reduce the increased mortality associated with delirium.
Assessment for differentiating depression as well as dementia is need
ed, because mistaken diagnoses often prolong and exacerbate the sympto
ms of delirium. Different treatment strategies are appropriate dependi
ng on the cause(s) of confusion. In this article, risk factors and ass
essment tools are reviewed, and interventions for delirium in older pe
rsons with cancer are presented. Future areas for research are identif
ied, because there is a paucity of research on delirium in older patie
nts with cancer.