SIMULTANEOUS DETERMINATION FROM INORGANIC ANIONS IN HUMAN FLUIDS - A NEW METHOD IN PEDIATRIC LABORATORY - RESULTS FROM A PILOT-STUDY

The anions analysis was a methodical problem up to now. This was the r eason for low interest. Biological fluids like saliva and urine which could easily receive without any stress for the children, are little i nvestigated for its capacity on nitrite, nitrate, bromide and sulfate. In this performance there will presented an ionchromatographic method e to determine inorganic anions in the following bodyfluids: serum sal iva, liquor and urine. The anions chloride, nitrite, bromide, nitrate, phosphate and sulfate was determined quantitativly. The methode was p roved in a pilotstudy on childrens bodyfluids serum, liquor and saliva . The objects was to get a landmark in exspectation from anion concent rations. Bromide was detected as a constant part in all body fluids. T he origin and importance is not clear till now. Also was found nitrate in all investigated body fluids. There seems to be a connection betwe en diarrhea and an increase in serum levels from nitrate. We found con siderable amounts of nitrate in saliva by babies and infants. The meth ode is distinguished by little fluctation in measurement and high spec ifity. Short time in analysis and simple handling will do the methode for a qualified one in pediatrics.