CHROMOSOMAL ASSIGNMENTS OF MOUSE GENES FOR CONNEXIN-50 AND CONNEXIN-33 BY SOMATIC-CELL HYBRIDIZATION

Authors
SCHWARZ HJ CHANG YS LALLEY PA WILLECKE K
Citation
Hj. Schwarz et al., CHROMOSOMAL ASSIGNMENTS OF MOUSE GENES FOR CONNEXIN-50 AND CONNEXIN-33 BY SOMATIC-CELL HYBRIDIZATION, Somatic cell and molecular genetics, 20(3), 1994, pp. 243-247
Citations number
19
Categorie Soggetti
Cytology & Histology","Genetics & Heredity",Biology
Journal title
Somatic cell and molecular genetics → ACNP
ISSN journal
07407750
Volume
20
Issue
3
Year of publication
1994
Pages
243 - 247
Database
ISI
SICI code
0740-7750(1994)20:3<243:CAOMGF>2.0.ZU;2-P
Abstract
The 12 known connexin genes coding for the subunit proteins of the gap junction channels and related in nucleotide sequence are widely dispe rsed in the mouse genome. By using a series of mouse x Chinese hamster somatic cell hybrids and molecular probes of murine connexin genes, w e have assigned the connexin 50 gene to mouse chromosome 3. The connex in 33 gene has been mapped to the X chromosome, thus confirming the pr evious chromosomal assignment of this gene based on interspecific back -cross mapping.