SYNTHESIS OF 6-AZIDO AND 6-AMINO ANALOGS OF 1-DEOXYNOJIRIMYCIN

Citation
A. Kilonda et al., SYNTHESIS OF 6-AZIDO AND 6-AMINO ANALOGS OF 1-DEOXYNOJIRIMYCIN, Journal of the Chemical Society, Chemical Communications, (18), 1994, pp. 2147-2148
Citations number
18
Categorie Soggetti
Chemistry
ISSN journal
00224936
Issue
18
Year of publication
1994
Pages
2147 - 2148
Database
ISI
SICI code
0022-4936(1994):18<2147:SO6A6A>2.0.ZU;2-6
Abstract
Selective isopropylidenation of the 2,3- and 5,6-hydroxy groups of 1-[ (tert-butoxycarbonyl)amino]-1-deoxy-D-glucitol 5b led to the diacetoni de 6 which was converted in seven steps to the selectively protected 6 -azido compound 3, a valuable precursor of various derivatives of 6-am ino-1,6-dideoxynojirimycin 4b.