DESIGN AND SYNTHESIS OF A NOVEL SITE-DIRECTED REDUCING AGENT FOR THE DISULFIDE BOND INVOLVED IN THE ACETYLCHOLINE BINDING-SITE OF THE ACHOR

Authors
KESSLER P SERVENT D HIRTH C
Citation
P. Kessler et al., DESIGN AND SYNTHESIS OF A NOVEL SITE-DIRECTED REDUCING AGENT FOR THE DISULFIDE BOND INVOLVED IN THE ACETYLCHOLINE BINDING-SITE OF THE ACHOR, Tetrahedron letters, 35(39), 1994, pp. 7237-7240
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
39
Year of publication
1994
Pages
7237 - 7240
Database
ISI
SICI code
0040-4039(1994)35:39<7237:DASOAN>2.0.ZU;2-8
Abstract
The thylammonioethyloxycarbonylamino-1,4-butanedithiol 7 was synthesiz ed and tested as a site-directed reducing agent for the disulfide bond involved in the acetylcholine binding site of the AChoR, which was th en specifically labeled by an undecagold cluster.