INCREASED FREQUENCY OF MICRONUCLEI IN LYMPHOCYTES OF SWEDISH CHIMNEY SWEEPS

Authors
HOLMEN A KARLSSON A BRATT I RAIHLE G HOGSTEDT B
Citation
A. Holmen et al., INCREASED FREQUENCY OF MICRONUCLEI IN LYMPHOCYTES OF SWEDISH CHIMNEY SWEEPS, International archives of occupational and environmental health, 66(3), 1994, pp. 185-187
Citations number
13
Categorie Soggetti
Public, Environmental & Occupation Heath
Journal title
International archives of occupational and environmental health → ACNP
ISSN journal
03400131
Volume
66
Issue
3
Year of publication
1994
Pages
185 - 187
Database
ISI
SICI code
0340-0131(1994)66:3<185:IFOMIL>2.0.ZU;2-Y
Abstract
Forty-five Swedish chimney sweeps and 49 controls were investigated wi th micronuclei stimulated by phytohemagglutinin and pokeweed mitogen a nd by analysis of lymphocyte subgroups and neutrophilic leukocytes. Th ere was a statistically significant effect among sweeps with respect t o both micronuclei variables and neutrophilic leukocytes. The effect o n lymphocyte micronuclei was most prominent in pokeweed mitogen-stimul ated cells, which may imply that the T4 lymphocytes were preferentiall y damaged by the occupational exposure.