Js. Fryburg et al., ABNORMAL HEAD MRI IN A NEUROLOGICALLY NORMAL BOY WITH HYPOMELANOSIS OF ITO, American journal of medical genetics, 66(2), 1996, pp. 200-203
We report on an 8.5-year-old boy with hypomelanosis of Ito (HI) who ha
s an abnormal MRI of the brain but is neurologically normal, There hav
e been many reports of abnormal brain imaging studies in patients with
HI, but all reported patients have had abnormal neurologic findings o
r symptoms, Our patient has had serial, stable head MRI white matter c
hanges and has remained neurologically normal without any neurologic s
equelae. (C) 1996 Wiley-Liss, Inc.