S. Pant et Uc. Pant, SYNTHESES OF 1,5-BENZOTHIAZEPINES .12. SYNTHESES OF -(4-TOLYLAMINO)-8-SUBSTITUTED-1,5-BENZOTHIAZEPINES, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 33(10), 1994, pp. 988-989
5-Substituted-2-aminobenzenethiols (1a-f) react with 4-(p-tolylamino)p
ent-3-en-2-one (2) in acidic medium, followed by neutralization and fu
rther addition of alkali, to yield, dro-2,4-dimethyl-2-(4-tolylamino)-
8-substituted-1, 5-benzothiazepines (3a-f). Elemental analyses, IR, H-
1 NMR and mass spectral data have been applied in assigning structures
to these compounds.