SYNTHESIS AND BIOLOGICAL EVALUATION OF DERIVATIVES OF (BUTYL,ARYL)-2,5-DIMETHYLPYRROLE-3,4-DICARBOXYMIDE .2.

Authors
MALINKA W SIEKLUCKADZIUBA M ROBAK J KLEINROK Z
Citation
W. Malinka et al., SYNTHESIS AND BIOLOGICAL EVALUATION OF DERIVATIVES OF (BUTYL,ARYL)-2,5-DIMETHYLPYRROLE-3,4-DICARBOXYMIDE .2., Il Farmaco, 49(7-8), 1994, pp. 481-487
Citations number
15
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Il Farmaco → ACNP
ISSN journal
0014827X
Volume
49
Issue
7-8
Year of publication
1994
Pages
481 - 487
Database
ISI
SICI code
0014-827X(1994)49:7-8<481:SABEOD>2.0.ZU;2-K
Abstract
A series of new ed-1-piperazinyl-alkyl]-3,4-pyrroledicarboxyimides 7 h ave been prepared by reaction of N-haloalkylimide derivatives 6 with c orresponding N-monosubstituted piperazines. Compounds 7 tested in prel iminary pharmacological investigation produced a general depressive ac tion on the central nervous system.