GENBANK

The GenBank sequence database continues to expand its data coverage, q uality control, annotation content and retrieval services for the scie ntific community. Besides handling direct submissions of sequence data from authors, GenBank also incorporates DNA sequences from all availa ble public sources; an integrated retrieval system, known as Entrez, a lso makes available data from the major protein sequence and structura l databases, and from U.S. and European patents. MEDLINE abstracts fro m published articles describing the sequences are also included as an additional source of biological annotation for sequence entries. GenBa nk supports distribution of the data via FTP, CD-ROM, and E-mail serve rs. Network server-client programs provide access to an integrated dat abase for literature retrieval and sequence similarity searching.