ACTION OF DICLOFENAC SODIUM ON THE REPARATION PROCESS OF THE SURGICALLY-PERFORATED MYOMETRIUM OF PREGNANT ALBINO-RATS - MORPHOLOGICAL AND MORPHOMETRICAL EVALUATION

1. The action of a non-hormonal anti-inflammatory agent on the reparat ion process of the surgically-perforated myometrium of pregnant albino rats was histologically evaluated. 2 On the 14th day after perforatio n, the muscular layers were still interrupted. 3. The morphological st udy was inconclusive. A morphometrical analysis, however, demonstrated that there was a meaningful diminution in the number of leucocytes an d collagen fibers and an increase in the number of fibroblasts, probab ly with low synthetical power, in the group treated with diclofenac so dium. All these data indicate a delay in the reparation process of the uterine musculature.