Kv. Krell et al., VASCULATURE OF THE DENTAL-PULP OF ATHEROSCLEROTIC MONKEYS - LIGHT ANDELECTRON-MICROSCOPIC FINDINGS, Journal of endodontics, 20(10), 1994, pp. 469-473
Arteriosclerosis is a pathological condition in which there is a sever
e luminal narrowing of arterioles, resulting in tissue ischemia and ne
crosis. Arteriosclerosis has been reported in the dental pulp of normo
tensive persons as young as 40 yr of age. To date, no corroboration of
these findings have been published. Our study examined pulp from athe
rosclerotic monkeys for such changes under controlled conditions. The
lingual artery and canines from 11 nonatherosclerotic (control) and 11
atherosclerotic (experimental) cynolmolgus monkeys were histologicall
y evaluated with light and transmission electron microscopy. Lingual a
rteries from controls did not exhibit atherosclerotic plaques, whereas
those of the experimental monkeys did show fibro-foamy plaques. Howev
er, neither experimental nor control animals exhibited any arteriolosc
lerotic alterations in the pulp. Our study concluded that, in this ani
mal model, which did demonstrate atherosclerosis in the oral cavity, n
o similar alterations were found in the pulp.