Purine metabolism disturbances which may be responsible for urate neph
ropathy were revealed in 35 % of the examinees with arterial hypertens
ion. Gout manifestations occurred in many of the above patients. Purin
e metabolism disturbances contribute much to progression of renal diso
rders and arterial hypertension, require early diagnosis and treatment
. Urate symptoms may serve a primary diagnostic indication.