A CONCISE SYNTHESIS OF (+ -)-MONOMORINE-I BY WAY OF A PALLADIUM-CATALYZED REDUCTIVE COUPLING/

Authors
CASTANO AM CUERVA JM ECHAVARREN AM
Citation
Am. Castano et al., A CONCISE SYNTHESIS OF (+ -)-MONOMORINE-I BY WAY OF A PALLADIUM-CATALYZED REDUCTIVE COUPLING/, Tetrahedron letters, 35(40), 1994, pp. 7435-7438
Citations number
30
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
40
Year of publication
1994
Pages
7435 - 7438
Database
ISI
SICI code
0040-4039(1994)35:40<7435:ACSO(->2.0.ZU;2-3
Abstract
A seven steps synthesis of the indolizidine alkaloid (+/-)-monomorine I is described starting from 2-methylpiperidine. The key step of the s ynthesis is a palladium-catalyzed reductive coupling reaction of an ac id chloride with a beta-stannanyl enone to give a 1,4-diketone.