Pj. Edwards et al., DISPIROKETALS IN SYNTHESIS .11. CONCOMITANT ENANTIOSELECTIVE AND REGIOSELECTIVE PROTECTION OF 2,5-DIBENZOYL-MYO-INOSITOL, Tetrahedron letters, 35(40), 1994, pp. 7443-7446
2,5-Dibenzoyl-myo-inositol, a symmetrical polyol, may be simultaneousl
y enantioselectively and regioselectively protected using the chiral d
ienes (1), (2) and (3). Deprotection, to afford D or L-1,6-tetra-O-ben
zyl-myo-inositol (8) and (12) respectively, was achieved using trifluo
roacetic acid.