MICELLAR ELECTROKINETIC CAPILLARY CHROMATOGRAPHY OF ALGAL TOXINS

Recent methods employed for the analysis of algal toxins have focused on high performance liquid chromatography. However these methods suffe r from poor resolution, poor efficiency, and long analysis times, This study involves the investigation of a number of toxins including nodu larin, microcystin LR, YR, and RR which are cyclic peptides produced b y strains of blue-green algae, The electroseparation mode was micellar electrokinetic capillary chromatography (MECC) using a berate buffer containing sodium dodecyl sulfate (SDS) as the surfactant of choice. T he method was optimized with standard toxin compounds and employed for the screening of toxins in supercritical fluid extracts (SFE) of free ze-thawed algal scum samples.