Aneurysms of the entire thoracic aorta are usually approached in two t
o three stages. From 1990 to 1994, we performed one-stage aortic repla
cement from the root to the diaphragm in 16 patients (8 men and 8 wome
n with a mean age of 55.7 years, range 49 to 73). There were 11 type A
dissections, 7 of which were acute. Six patients underwent aortic val
ve reconstruction; seven had aortic root replacement by Bentall or Cab
rol techniques. In two cases, the innominate artery had to be replaced
by a vascular graft separately in addition to reimplantation of the s
upraaortic branches as an island flap into the arch prosthesis. In eig
ht cases, a median sternotomy was used; eight had a bilateral transver
se thoracotomy. The procedure was performed under deep hypothermic cir
culatory arrest in all cases (mean duration 50.5 min, range 38 to 62 m
in). Two patients, both operated upon for an acute dissection, expired
perioperatively: one due to a bronchopneumonia, and one because of a
thrombosed Cabrol graft to the right coronary artery. No patient devel
oped bleeding or neurological complications. At a mean follow-up of 26
.9 months (1 to 50 months), all patients discharged from the hospital
were still alive. Four patients underwent subsequent thoracoabdominal
aortic replacement. This experience suggests that complete thoracic ao
rtic replacement can be performed in a single session with an operativ
e risk comparable to that of the conventional two-stage approach. The
bilateral transverse thoracotomy affords excellent exposure. The lack
of spinal cord ischemia may be the result of spinal cord protection wi
th hypothermic circulatory arrest and use of the open-clamp technique.