PECULIARITIES OF CHANGES IN THE RATE OF CHOLESTEROL-SYNTHESIS IN LYMPHOCYTES AND LIPID AND LIPOPROTEIN PERIPHERAL-BLOOD LEVELS IN PATIENTS WITH ISCHEMIC-HEART-DISEASE AND HYPERCHOLESTEROLEMIA IN THE COURSE OF COMBINED TREATMENT WITH LOVASTATIN AND OBSIDAN

Authors
POLYAKOVA ED IVANOVA TN NIKULINA SE METELSKAYA VA OLFEREV AM SHCHERBAKOVA IA AKHMEDZHANOV NM PEROVA NV
Citation
Ed. Polyakova et al., PECULIARITIES OF CHANGES IN THE RATE OF CHOLESTEROL-SYNTHESIS IN LYMPHOCYTES AND LIPID AND LIPOPROTEIN PERIPHERAL-BLOOD LEVELS IN PATIENTS WITH ISCHEMIC-HEART-DISEASE AND HYPERCHOLESTEROLEMIA IN THE COURSE OF COMBINED TREATMENT WITH LOVASTATIN AND OBSIDAN, Bulletin of experimental biology and medicine, 117(3), 1994, pp. 249-252
Citations number
15
Categorie Soggetti
Medicine, Research & Experimental
Journal title
Bulletin of experimental biology and medicine → ACNP
ISSN journal
00074888
Volume
117
Issue
3
Year of publication
1994
Pages
249 - 252
Database
ISI
SICI code
0007-4888(1994)117:3<249:POCITR>2.0.ZU;2-H
Abstract
It is shown that the level of total serum cholesterol dropped and the rate of cholesterol synthesis in lymphocytes remained unchanged after 12 months of lovastatin treatment (20 mg/day) in patients with coronar y heart disease. The administration of lovastatin abolished the delete rious effect of obsidan on the blood lipid spectrum.