Vp. Fedotov et al., AGE-SPECIFIC EFFECTS OF INSULIN ON THE SECRETION OF SOMATOTROPIC HORMONE, Bulletin of experimental biology and medicine, 117(3), 1994, pp. 307-310
It is shown that insulin is able to alter the secretion of somatotropi
c hormone directly at the level of the pituitary. The direction of the
regulatory effect of insulin depends on the age of the animals donati
ng the pituitary cells, while the intensity of the effect of insulin i
s largely modulated by glucocorticoid and thyroid hormone.