Ag. Zakharov et al., EFFECT OF NO-SPA ON THE STATE OF ARTERIOLES OF THE SKELETAL-MUSCLE OFRATS AFTER TOTAL IRRADIATION WITH 1 GY, Bulletin of experimental biology and medicine, 117(3), 1994, pp. 321-322
Intraarterial injection of 1, 2, and 3 mg/kg No-spa is shown to cause
a dose-independent dilation of arterioles, averaging 27.4% in the cont
rol animals, On day 6 postirradiation the dilative responses of arteri
oles drop to 21.1% (p<0.05), which is due to suppression of the myogen
ic tone of the microvessels.