Bone marrow necrosis is an uncommon histologic finding of malignant di
seases at presentation. Clinically it is characterized by pyrexia and
severe bone pain, and heralds a poor prognosis if untreated. We report
an unusual patient with asymptomatic bone marrow necrosis persisting
for 10 mths, a hitherto undescribed length of time for this condition.
The diagnosis of Philadelphia chromosome positive acute lymphoblastic
leukemia was finally made after multiple bone marrow biopsies.