PHILADELPHIA-CHROMOSOME-POSITIVE ACUTE LYMPHOBLASTIC-LEUKEMIA MASQUERADING AS PERSISTENT ASYMPTOMATIC BONE-MARROW NECROSIS

Citation
Yl. Kwong et al., PHILADELPHIA-CHROMOSOME-POSITIVE ACUTE LYMPHOBLASTIC-LEUKEMIA MASQUERADING AS PERSISTENT ASYMPTOMATIC BONE-MARROW NECROSIS, Pathology, 26(2), 1994, pp. 183-185
Citations number
16
Categorie Soggetti
Pathology
Journal title
ISSN journal
00313025
Volume
26
Issue
2
Year of publication
1994
Pages
183 - 185
Database
ISI
SICI code
0031-3025(1994)26:2<183:PALM>2.0.ZU;2-S
Abstract
Bone marrow necrosis is an uncommon histologic finding of malignant di seases at presentation. Clinically it is characterized by pyrexia and severe bone pain, and heralds a poor prognosis if untreated. We report an unusual patient with asymptomatic bone marrow necrosis persisting for 10 mths, a hitherto undescribed length of time for this condition. The diagnosis of Philadelphia chromosome positive acute lymphoblastic leukemia was finally made after multiple bone marrow biopsies.