TOXICITY ASSOCIATED WITH SEVERE INHALATIONAL AND DERMAL EXPOSURE TO DIMETHYLACETAMIDE AND 1,2-ETHANEDIAMINE

We present the case of a worker who was accidentally exposed (inhalati onal and dermal routes) to the chemicals dimethylacetamide and ethylen ediamine for 90 minutes in a confined space. Clinical effects included delirium, hallucinations, skin burns, cellulitis, bilateral conjuncti vitis, hepatitis, secondary coagulopathy, rhabdomyolysis, and a grade 2 esophagitis. Urinary monomethylacetamide levels 6 days after the exp osure were 61 ppm.