L. Andersson et B. Hagmar, FINE-NEEDLE ASPIRATION BIOPSY FOR DIAGNOSIS AND FOLLOW-UP OF PROSTATE-CANCER, Scandinavian journal of urology and nephrology, 1994, pp. 43-49
Fine needle aspiration biopsy (FNAB) and ultrasound-guided core biopsy
using biopty gun both have a high, and approximately equal, accuracy
in diagnosing and grading prostate cancer. The TRUS-guided technique p
rovides a better estimation of the tumor extent and to some degree eve
n of capsular involvement. It is therefore a recommendable part of the
preoperative evaluation when radical prostatectomy is contemplated. O
n the other hand, the aspiration technique usually provides more epith
elial cells. It entails a significantly lower risk of septic complicat
ions and of seeding tumor cells. It has also a lower cost than the cor
e biopsies. The aspiration biopsy can easily be performed repeatedly i
n the follow-up procedure, which is of particular importance in cases
managed with watchful waiting. We recommend the aspiration biopsy for
routine use in the diagnostic work-up and follow-up. It is essential t
hat not only the cytologic evaluation but as well the sampling from th
e prostate is performed with adequate expertise.