The pathogenetic mechanism of tension headache (TH) is still unknown.
The role of pericranial muscle tension in TH is also enigmatic. To eva
luate this factor in chronic TH, pericranial muscles were paralysed in
6 chronic TH patients, using botulinum toxin. All patients fulfilled
the IHS criteria of chronic TH associated with involvement of the peri
cranial muscles, but not the current criteria for cervicogenic headach
e. The patients were followed-up regularly with evaluation of the para
lysis, changes in pain intensity, and pressure pain threshold measurem
ents. We primarily only injected the temporal muscle on the one side,
using the other side as a control. Contralateral muscles were in some
cases injected at a later stage. In our study, we did not find any sig
nificant reduction in pain intensity, as measured by the visual analog
ue scale, nor any changes in pressure pain threshold, as measured by a
n algometer. On the basis of our observations, we conclude that muscle
tension in these muscles possibly plays a minor role in the genesis o
f chronic TH. In our study, however, we have only treated a limited nu
mber of patients, and only one pericranial muscle has been injected sy
stematically. Further studies of various neck/posterior head muscles o
ught to be performed in order to furth er evaluate a possible eff ect
of tension in the pericranial musculature in producing this type of pa
in.