TARGET MODEL OF NUCLEOSOME PARTICLE FOR TRACK STRUCTURE CALCULATIONS AND DNA-DAMAGE MODELING

Authors
MICHALIK V BEGUSOVA M
Citation
V. Michalik et M. Begusova, TARGET MODEL OF NUCLEOSOME PARTICLE FOR TRACK STRUCTURE CALCULATIONS AND DNA-DAMAGE MODELING, International journal of radiation biology, 66(3), 1994, pp. 267-277
Citations number
39
Categorie Soggetti
Radiology,Nuclear Medicine & Medical Imaging","Nuclear Sciences & Tecnology
Journal title
International journal of radiation biology → ACNP
ISSN journal
09553002
Volume
66
Issue
3
Year of publication
1994
Pages
267 - 277
Database
ISI
SICI code
0955-3002(1994)66:3<267:TMONPF>2.0.ZU;2-G
Abstract
A non-homogeneous target model of nucleosome particle for track struct ure calculations and biophysical modelling of radiation-induced DNA da mage was developed together with a sampling method for non-homogeneous targets. The model allows one to distinguish energy deposited in the histone core, primary hydration shell and nucleosome DNA. Illustrative results for low energy electrons are presented and compared with resu lts obtained with simpler models of a nucleosome particle.