The factors affecting the growth of most common filamentous microorgan
isms are discussed. In a design procedure the following factors should
be considered: wastewater composition (readily and slowly biodegradab
le substrates, inoculation), biomass retention time, actual substrate
concentration in reactor, operational parameters in reactor (DO and nu
trients concentration, pH, temperature) and cultivation conditions. Th
e configurations of activated sludge process supporting the growth of
floc-formers are described. As general design methods and criteria for
the design of bulking control systems are not available due to the co
mplexity of selection mechanisms, the technological parameters from su
ccessful bulking control case histories are summarized. The possibilit
ies of mathematical activated sludge process models for design purpose
s are evaluated.