Br. Williams et al., A RETROSPECTIVE STUDY OF THE DIAGNOSTIC-ACCURACY OF A COMMUNITY HOSPITAL-BASED PET CENTER FOR THE DETECTION OF CORONARY-ARTERY DISEASE USING RB-82, The Journal of nuclear medicine, 35(10), 1994, pp. 1586-1592
A retrospective analysis has been carried out to determine the diagnos
tic accuracy of PET of the heart with Rb-82 at a community hospital ba
sed center. Methods: Utilization statistics were derived from a total
of 1460 patients scanned for the first 36 mo of the center's operation
. Diagnostic accuracy for detection of coronary artery disease (CAD) w
as assessed using three readers blinded to the clinical information. A
total of 287 rest and dipyridamole-stress scans of patients who had c
oronary angiograms within 6 mo of the PET scan were selected by the co
mputer for this study. Each rest/stress scan was read by at least two
of the three readers. Results: The average sensitivity for all three r
eaders was 87% for greater than 67% diameter stenosis and the average
specificity was 88% for myocardial regions perfused by normal coronary
arteries. The average accuracy was 88% for patients with greater than
67% diameter stenosis. Sensitivity and accuracy improved to 92% and 9
1% respectively for stenosis greater than 90% in diameter. Conclusion:
These results compare well with published results from major hospital
-based centers and the recently published results from a private PET c
enter in Georgia.