ACCESS TO 2-FLUOROACRYLATES AND THEIR 3-CHLORO DERIVATIVES BY CHEMICAL HYDROGENOLYSIS OF 3,3-DICHLORO-2-FLUOROACRYLATES

Authors
NGUYEN T WAKSELMAN C
Citation
T. Nguyen et C. Wakselman, ACCESS TO 2-FLUOROACRYLATES AND THEIR 3-CHLORO DERIVATIVES BY CHEMICAL HYDROGENOLYSIS OF 3,3-DICHLORO-2-FLUOROACRYLATES, Journal of fluorine chemistry, 80(2), 1996, pp. 95-99
Citations number
25
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear
Journal title
Journal of fluorine chemistry → ACNP
ISSN journal
00221139
Volume
80
Issue
2
Year of publication
1996
Pages
95 - 99
Database
ISI
SICI code
0022-1139(1996)80:2<95:AT2AT3>2.0.ZU;2-M
Abstract
The formation of 3-chloro-2-fluoroacrylates 2 and 2-fluoroacrylates 3 by hydrogenolysis of 3,3-dichloro-2-fluoroacrylates 1 was studied by u sing Bu(3)SnH, zinc, the sodium sulphite/sodium formate mixture or iro n pentacarbonyl in the presence of a hydrogen donor (Et(3)SiH or CH,OH ). The two last couples can be used to prepare the 3-chloro derivative s 2, whereas for the preparation of the 3,3-dihydro derivatives 3, zin c is the most appropriate reducing agent.