MALIGNANT T-CELL LYMPHOMA ASSOCIATED WITH SARCOIDOSIS

We report an unusual case of non-Hodgkin T cell lymphoma associated wi th sarcoidosis. A 44-year-old woman was histologically diagnosed as ha ving sarcoidosis in 1966. Diffuse interstitial lung disease and erythe matous skin nodules disappeared following steroid therapy. Twenty year s after sarcoidosis onset erythematous nodosum recurred and biopsy spe cimens revealed non caseating epithelioid granuloma. Thirty-seven mont hs later a malignant T cell lymphoma developed in the skin portion whe re sarcoid lesions recurred. We discuss the possible relationship betw een the sarcoid inflammatory process and the development of a malignan t T cell clone as origin of the T cell lymphoma.