CHILDHOOD SARCOIDOSIS PRESENTING WITH HYPERCALCEMIC CRISIS

We report a case of hypercalcaemic crisis due to sarcoidosis in a 15-y ear-old boy. The clinical suspicion of sarcoidosis was confirmed by a liver biopsy. At admission serum calcium, 1,25(OH)2 and ACE were eleva ted and iPTH was suppressed. The levels of serum total and ionized cal cium, iPTH, ACE, 1,25-(OH)2 and 25-OH were followed and chest X-ray an d pulmonary function tests were performed during systemic steroid trea tment. The clinical condition improved during treatment and the paracl inical measurements normalised within 5 weeks. The mechanism whereby h ypercalcaemia occurs in childhood sarcoidosis is clarified.