THEOPHYLLINE SALIVARY AND SERUM CONCENTRA TIONS IN PATIENTS WITH BRONCHOOBSTRUCTIVE SYNDROME AND RELEVANT CORRELATIONS

Authors
TSOI AN GAVRILENKO LN KUSHKENBAEVA BY KUKES VG
Citation
An. Tsoi et al., THEOPHYLLINE SALIVARY AND SERUM CONCENTRA TIONS IN PATIENTS WITH BRONCHOOBSTRUCTIVE SYNDROME AND RELEVANT CORRELATIONS, Terapevticeskij arhiv, 66(8), 1994, pp. 42-44
Citations number
23
Categorie Soggetti
Medicine, General & Internal
Journal title
Terapevticeskij arhiv → ACNP
ISSN journal
00403660
Volume
66
Issue
8
Year of publication
1994
Pages
42 - 44
Database
ISI
SICI code
0040-3660(1994)66:8<42:TSASCT>2.0.ZU;2-K
Abstract
Theophylline salivary and serum concentrations (T(ser) and T(sal) were quantified after a single dose administration of theophylline drugs: euphylline (2.4% solution, 10 ml i.v. jet and 0.15 orally), theo-dur, retaphil, theopek, theobilong (0.3 g orally). The drugs were given to patients with bronchoobstructive syndrome. The samples were obtained w ithin 6 and 24 hours upon administration for euphylline and other drug s, respectively. T(ser) and T(sal) were determined at high-performance liquid chromatography. The authors revealed a linear relationship bet ween T(ser) and T(sal) in different time intervals. The percentage fac tors and formulas of T(ser) calculation by its T(sal) values have been estimated.