VARIABILITY OF ARTERIAL-PRESSURE IN MILD ARTERIAL-PRESSURE - EVIDENCEOF 24-H MONITORING

To evaluate the condition of target-organs in patients with mild arter ial hypertension (MAH) under normal and high arterial pressure variabi lity (APV), the authors examined 84 MAH males aged 40-60 and 14 matche d healthy controls. At 24-h monitoring it was revealed that 32% of MAH patients had high variability of day-time and night arterial pressure which occurred more frequently in atherosclerotic lesion of extracran ial carotid artery portions. MAH patients with high APV against those with normal APV develop carotid artery atherosclerosis 3,5 times more frequently, vascular disorders of the fundus of the eye stage II with angiosclerosis and thickening of the interventricular septum 2,5 and 1 ,8 times more frequently, respectively.