G. Gozzetti et al., FUNCTIONAL OUTCOME IN HANDSEWN VERSUS STAPLED ILEAL POUCH-ANAL ANASTOMOSIS, The American journal of surgery, 168(4), 1994, pp. 325-329
Eighty-eight of 119 patients who underwent ileal pouch-anal anastomosi
s for ulcerative colitis were evaluated. Forty patients had a handsewn
anastomosis (Hs) with mucosectomy, and 48 had a stapled anastomosis (
St). In each patient, we evaluated operative, morphologic, functional,
and manometric features. The results in the Hs and St groups were sim
ilar when the anastomosis was within 1 cm of the dentate line. In part
icular, there was no correlation between the type of anastomosis and t
he number of bowel movements in a 24-hour period, the presence of the
urge to defecate, and the use of antidiarrheal drugs. Leakage was sign
ificantly higher in the Hs group, even when the anastomosis was less t
han 1 cm from the dentate line. Pouchitis was more frequent in the Hs
group, and, within this group, among those with a short distance betwe
en the anastomosis and the dentate line. No correlations were found be
tween the presence of columnar epithelium or active colitis in the col
umnar epithelium or active colitis in the mucosa below the anastomosis
, the functional outcomes, and the incidence of pouchitis.