P. Speers et al., ORIGINS OF THE ACIDITY TRENDS IN DIMETHYL SULFIDE, DIMETHYL-SULFOXIDE, AND DIMETHYL SULFONE, Journal of the American Chemical Society, 116(20), 1994, pp. 9257-9261
We present a theoretical study into the origin of the acidity trends i
n the series dimethyl sulfide (Dh?MS), dimethyl sulfoxide (DMSO), and
dimethylsulfone (DMSO(2)). Calculations at the HF/6-31++G*//HF/6-31+G* level of theory reproduce the observed acidity trend, DMSO(2) > DM
SO > DMS. The relative acidity is found to be an inherent property of
the acid and the relative stability and geometric relaxation within th
e anion are unimportant. Detailed investigation of the energetics at t
he atomic level reveals that the origin of the relative acidities with
in the series is a greater destabilization of the CH3SCH2 fragment in
the acid with increasing oxygen substitution than in the associated an
ion. We find no evidence in the atomic properties and the topological
properties of the charge density for an appreciable delocalization of
charge from the anionic carbon in the anion.