A 46-year-old man presented with right upper quadrant pain with a clin
ical suspicion of cholelithiasis and was referred for an abdominal ult
rasound (US). On US evaluation, the liver and gallbladder were normal.
Incidentally noted a homogeneous, well demarcated, hyperechoic, 5-cm
mass in the inferior portion of the spleen. A subsequent Tc-99m labele
d RBC scan showed a 5-cm photopenic area in the inferior portion of th
e spleen on perfusion and early blood pool images. Subsequent filling
in on delayed images with slightly increased uptake relative to surrou
nding splenic tissue was seen on the final images (85 min). Splenic he
mangiomas are rare neoplasms, although they still represent the most c
ommon primary neoplasm of the spleen. The incidence of splenic hemangi
omas ranges from 0.03-14% in autopsy studies.