USE OF SCANNING ELECTRON-MICROSCOPY IN THE STUDY OF NEPHROTOXIN-INDUCED RENAL PROXIMAL TUBULAR DAMAGE IN-VITRO

Authors
REES JA EVANS JG BLACKMORE M SPENCER AJ GRAY TJB
Citation
Ja. Rees et al., USE OF SCANNING ELECTRON-MICROSCOPY IN THE STUDY OF NEPHROTOXIN-INDUCED RENAL PROXIMAL TUBULAR DAMAGE IN-VITRO, Toxicology in vitro, 8(4), 1994, pp. 601-603
Citations number
3
Categorie Soggetti
Toxicology
Journal title
Toxicology in vitro → ACNP
ISSN journal
08872333
Volume
8
Issue
4
Year of publication
1994
Pages
601 - 603
Database
ISI
SICI code
0887-2333(1994)8:4<601:UOSEIT>2.0.ZU;2-#
Abstract
Scanning electron microscopy was used to study cephaloridine and genta micin-induced renal cell injury in vitro. Exposure of renal proximal t ubular cells to these toxicants produced changes in cell surface morph ology that occurred at concentrations similar to (or below) those affe cting neutral red uptake or monolayer permeability.