CHEMISTRY OF AZIRIDINECARBOXYLIC ACIDS .4 . ENANTIOSELECTIVE HYDRATION OF AZIRIDINE-2-CARBONITRILE

Authors
JAHNISCH K GRUNDEMANN E KUNATH A RAMM M
Citation
K. Jahnisch et al., CHEMISTRY OF AZIRIDINECARBOXYLIC ACIDS .4 . ENANTIOSELECTIVE HYDRATION OF AZIRIDINE-2-CARBONITRILE, Liebigs Annalen der Chemie, (9), 1994, pp. 881-883
Citations number
11
Categorie Soggetti
Chemistry
Journal title
Liebigs Annalen der Chemie → ACNP
ISSN journal
01702041
Issue
9
Year of publication
1994
Pages
881 - 883
Database
ISI
SICI code
0170-2041(1994):9<881:COAA..>2.0.ZU;2-A
Abstract
Aziridine-2-carbonitrile rac-1 was hydrated enantioselectively in aque ous medium by using methylethyl)-2-methyl-3-oxocyclohexanecarbonitrile (2) as chiral catalyst. The ee value of the unreacted (S)-(-)-aziridi ne-2-carbonitrile 1 depends on the conversion and reaches greater than or equal to 99%.