We describe an 11-year-old girl with secondary anetoderma involving a
pilomatricoma. She presented with a soft, wrinkled pedunculated lesion
overlying a firm subcutaneous mass on her right anterior shoulder. Pa
thologic examination revealed a pilomatricoma in the subcutaneous tiss
ue, with focal loss of elastic fibers in the overlying dermis. Seconda
ry anetoderma has been reported to involve various infections, inflamm
atory disorders, and tumors, but the association with pilomatricoma is
very rare.