M. Nakamuta et al., ORAL CONTRACEPTIVE-DEPENDENT GROWTH OF FOCAL NODULAR HYPERPLASIA, Journal of gastroenterology and hepatology, 9(5), 1994, pp. 521-523
A 22 year old woman was incidentally found to have a hepatic small hae
mangioma-like mass, measuring 1.4 cm in diameter, by an ultrasonograph
ic examination. The mass demonstrated no change in size or appearance
for 6 months until the patient began to take oral contraceptives. Even
tually, the mass increased to 2.0 cm in diameter after using oral cont
raceptives for 6 months. A histological examination suggested the mass
to be typical focal nodular hyperplasia, and not hepatic adenoma. The
re was no further change in either size or appearance in the ensuing 1
year after the discontinuation of oral contraceptives.