SYNTHESIS OF 1,3-THIAZOLINE DERIVATIVES FROM BETA-DICARBONYL COMPOUNDS AND PHENACYL THIOCYANATE

Authors
DOROKHOV VA GORDEEV MF SHASHKOVA EM BOGDANOV VS
Citation
Va. Dorokhov et al., SYNTHESIS OF 1,3-THIAZOLINE DERIVATIVES FROM BETA-DICARBONYL COMPOUNDS AND PHENACYL THIOCYANATE, Russian chemical bulletin, 42(11), 1993, pp. 1854-1856
Citations number
4
Categorie Soggetti
Chemistry
Journal title
Russian chemical bulletin → ACNP
ISSN journal
10665285
Volume
42
Issue
11
Year of publication
1993
Pages
1854 - 1856
Database
ISI
SICI code
1066-5285(1993)42:11<1854:SO1DFB>2.0.ZU;2-6
Abstract
Acetylacetone and ethyl acetoacetate undergo addition at the C=N bond of phenacyl thiocyanate in the presence of Ni(acac)2 to give the respe ctive ketene N,S-acetals, which undergo smooth cyclization to afford 2 -methylene-4-phenyl-1,3-thiazoline derivatives when refluxed in THF.