HYDROGENATION OF PYRROLE DERIVATIVES .2. HYDROGENATIONS OVER SUPPORTED NOBLE-METAL CATALYSTS

Authors
HEGEDUS L MATHE T TUNGLER A
Citation
L. Hegedus et al., HYDROGENATION OF PYRROLE DERIVATIVES .2. HYDROGENATIONS OVER SUPPORTED NOBLE-METAL CATALYSTS, Applied catalysis. A, General, 147(2), 1996, pp. 407-414
Citations number
7
Categorie Soggetti
Chemistry Physical","Environmental Sciences
Journal title
Applied catalysis. A, General → ACNP
ISSN journal
0926860X
Volume
147
Issue
2
Year of publication
1996
Pages
407 - 414
Database
ISI
SICI code
0926-860X(1996)147:2<407:HOPD.H>2.0.ZU;2-A
Abstract
The heterogeneous catalytic hydrogenation of 1-methyl-2-pyrroleethanol resulted in 1-methyl-2-pyrrolidineethanol, an important and valuable pharmaceutical intermediate. Various noble metal catalysts on differen t supports have been screened. The best results were achieved with a c arbon supported rhodium catalyst, in non-acidic medium, under mild rea ction conditions (6 bar, room temperature). Ruthenium on carbon also s howed high activity in this hydrogenation.